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Transcription Factors HNF1A, HNF4A, and FOXA2 Regulate Hepatic Cell Protein N-Glycosylation Article

Vedrana Vičić Bočkor,Nika Foglar,Goran Josipović,Marija Klasić,Ana Vujić,Branimir Plavša,Toma Keser,Samira Smajlović,Aleksandar Vojta,Vlatka Zoldoš

Engineering 2024, Volume 32, Issue 1,   Pages 58-69 doi: 10.1016/j.eng.2023.09.019

Abstract:

Hepatocyte nuclear factor 1 alpha (HNF1A), hepatocyte nuclear factor 4 alpha (HNF4A), and forkheadOur in silico analysis of HNF1A, HNF4A, and FOXA2 binding to the 10 candidate glyco-genes studiedshort palindromic repeats/dead Cas9 (CRISPR/dCas9) molecular tool for the downregulation of the HNF1A, HNF4A, and FOXA2 genes in HepG2 cells—a human liver cancer cell line.We also propose a model showing feedback loops with the mutual activation of HNF1A–FOXA2 and HNF4A

Keywords： Clustered regularly interspaced short palindromic repeats/dead Cas9 (CRISPR/dCas9)     Epigenetics     Hepatocytenuclear factor 1 alpha (HNF1A)     Hepatocyte nuclear factor 4 alpha (HNF4A)     Forkhead box protein A2 (    

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Relationship between expression of hepatocyte grow factor and apoptosis of trophoblasts in hypertensive

OUYANG Shan, ZHANG Qinghua, QIAO Fuyuan

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 386-389 doi: 10.1007/s11684-007-0075-6

Abstract: The aim of this study was to investigate the expression of hepatocyte growth factor (HGF) and Fas in

Keywords： pregnancy     concentration     possible relationship     responsible     hepatocyte    

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carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor4A-I

Frontiers of Medicine 2023, Volume 17, Issue 3,   Pages 476-492 doi: 10.1007/s11684-022-0966-6

Abstract: knockdown yielded opposite results. 5′-tiRNA-Gln exerted its function by binding eukaryotic initiation factor4A-I (EIF4A1), which unwinds complex RNA secondary structures during translation initiation, causingsequence of forming intramolecular G-quadruplex structure is crucial for 5′-tiRNA-Gln to strongly bind EIF4A1Collectively, these findings reveal that 5′-tiRNA-Gln interacts with EIF4A1 to reduce related mRNA binding

Keywords： EIF4A1     G-quadruplex     hepatocellular carcinoma     tRNA-derived small RNA     translation initiation    

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DDB1- and CUL4-associated factor 8 plays a critical role in spermatogenesis

Xiuli Zhang, Zhizhou Xia, Xingyu Lv, Donghe Li, Mingzhu Liu, Ruihong Zhang, Tong Ji, Ping Liu, Ruibao Ren

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 302-312 doi: 10.1007/s11684-021-0851-8

Abstract: Cullin-RING E3 ubiquitin ligase (CRL)-4 is a member of the large CRL family in eukaryotes.DDB1- and CUL4-associated factor 8 (DCAF8) is a WD40 repeat-containing protein, which serves as a substratereceptor for CRL4.demonstrated that DCAF8 plays a critical role in spermatogenesis, and DCAF8 is a key component of CRL4

Keywords： Dcaf8     male infertility     spermatogenesis    

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ZnFe2O4/BiVO4 Z-scheme heterojunction for efficient visible-light photocatalytic

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 11,   Pages 1728-1740 doi: 10.1007/s11705-023-2322-z

Abstract: A novel Z-scheme ZnFe2O4/BiVO4 heterojunction photocatalyst was successfullyCompared with the single-phase counterparts, ZnFe2O4/BiVO4 demonstratedConsequently, the 30% ZnFe2O4/BiVO4 catalyst afforded a degradationorganic carbon removal rate of 50%, which is an excellent activity compared with ever reported BiVO42O4/BiVO4 heterojunctions were quite

Keywords： ZnFe2O4/BiVO4     Z-scheme heterojunction     photocatalytic degradation    

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Inhibition of TNF-alpha secretion from peripheral blood monocular cells by triptolid is associated withTNF-alpha-308 gene polymorphisms in rheumatoid arthritis patients

Xiu-Liang TAO MM, Sheng-Hao TU MD, Ri-Bo XIONG MM, Yong-Hong HU BM,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 220-224 doi: 10.1007/s11684-010-0025-6

Abstract: This study examined the inhibitory effect of triptolid (TP) on tumor necrosis factor-α (TNF-α

Keywords： arthritis     rheumatoid     molonuclear cells     tumor necrosis factor     gene polymorphisms     triptolid    

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Li4SiO4-coated LiNi0.5Mn1.5O4 as the high performance

Shifeng YANG, Wenfeng REN, Jian CHEN

Frontiers in Energy 2017, Volume 11, Issue 3,   Pages 374-382 doi: 10.1007/s11708-017-0494-2

Abstract: The preparation of Li SiO -coated LiNi Mn O materials by sintering the SiO -coated nickel-manganese oxides with lithium salts using abundant and low-cost sodium silicate as the silicon source was reported. The samples were characterized by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. It was found that a uniform and complete SiO coating layer could be obtained at a suitable pH value of 10, which transformed to a good Li SiO coating layer afterwards. When used as the cathode materials for lithium-ion batteries, the Li SiO -coated LiNi Mn O samples deliver a better electrochemical performance in terms of the discharge capacity, rate capability, and cycling stability than that of the pristine material. It can still deliver 111.1 mAh/g at 20 C after 300 cycles, with a retention ratio of 93.1% of the stable capacity, which is far beyond that of the pristine material (101.3 mAh/g, 85.6%).

Keywords： lithium-ion batteries     cathode material     LiNi0.5Mn1.5O4     lithium-ion conductor    

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Enhanced debromination of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) by zero-valent zinc with ascorbic

Chaojin Jiang, Xiaoqian Jiang, Lixun Zhang, Yuntao Guan

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 3, doi: 10.1007/s11783-020-1224-2

Abstract: zero-valent zinc coupled with ascorbic acid (ZVZ/AA) was developed and applied to debrominate the 2,2′,4,4ZVZ particles and 3 mmol/L AA at original solution pH= 4.00 using the solvent of methanol/H2O (v:v= 4:

Keywords： 2     2′     4     4′-tetrabromodiphenyl ether (BDE-47)     Ascorbic acid     Reductive debromination     Zero-valent zinc    

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Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma and

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 132-142 doi: 10.1007/s11684-022-0938-x

Abstract: In the present study, replication factor c subunit 4 (RFC4) is a key potential target involved in NPCFurthermore, the expression and mechanism of RFC4 in NPC were investigated in vitro and inOur results revealed that RFC4 was more elevated in NPC tumor tissues than in normal tissues.RFC4 knockdown induced G2/M cell cycle arrest and inhibited NPC cell proliferation in vitro andInterestingly, HOXA10 was confirmed as a downstream target of RFC4, and the overexpression of HOXA10

Keywords： nasopharyngeal carcinoma     WGCNA     RFC4     proliferation    

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Laws of 4D Printing Article

Farhang Momeni, Jun Ni

Engineering 2020, Volume 6, Issue 9,   Pages 1035-1055 doi: 10.1016/j.eng.2020.01.015

Abstract: Accordingly, four-dimensional (4D) printing is a manufacturing process that involves multiple researchfields. 4D printing conserves the general attributes of 3D printing (such as material waste reductionThe main difference between 3D- and 4D-printed structures is the presence of one additional dimensionshow that two types of time constants are needed to capture the correct time-dependent behavior of 4Dintroduce the concept of mismatch-driven stress at the interface of active and passive materials in 4D

Keywords： Manufacturing     Stimuli-responsive materials     Mechanics of materials     Time constant     4D printing    

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Synthesis, insecticidal activities and DFT study of pyrimidin-4-amine derivatives containing the 1,2,4

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 7,   Pages 1090-1100 doi: 10.1007/s11705-021-2091-5

Abstract: Twenty six novel pyrimidin-4-amine derivatives containing the 1,2,4-oxadiazole motif were synthesizedTheir chemical structures were confirmed by 1H nuclear magnetic resonance (NMR), 13

Keywords： synthesis     pyrimidin-4-amine derivatives     1     2     4-oxadiazole     insecticidal activity     structure-activity    

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Identifying stakeholders’ roles and relevant project documents for 4D-based collaborative decision making

Veronika BOLSHAKOVA, Annie GUERRIERO, Gilles HALIN

Frontiers of Engineering Management 2020, Volume 7, Issue 1,   Pages 104-118 doi: 10.1007/s42524-019-0041-4

Abstract: To fully understand and effectively implement 4D building information modelling (BIM) models and methodsThis article studies the convergence between uses of 4D BIM and digital project documents.We hypothesize that a clear visualization of the construction simulation through a 4D model is a usefulIt then introduces a proposition for 4D BIM uses implementation by the project development phase.It concludes by summarizing stakeholders’ roles and documents relevant to 4D BIM uses.

Keywords： BIM     4D BIM     4D BIM use     AEC project management     collaboration     decision making    

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Review of 4Pi Fluorescence Nanoscopy Review

Xiang Hao, Yiming Li, Shuang Fu, Yanghui Li, Yingke Xu, Cuifang Kuang, Xu Liu

Engineering 2022, Volume 11, Issue 4,   Pages 146-153 doi: 10.1016/j.eng.2020.07.028

Abstract: An important milestone in this pursuit is the coherent utilization of two opposing objectives (4Pi geometryHerein, we review the recent progress in 4Pi nanoscopy, which provides a 3D, non-invasive, diffraction-unlimitedThis review includes both the targeted and stochastic switching modalities of 4Pi nanoscopy.The schematics, principles, applications, and future potential of 4Pi nanoscopy are discussed in detail

Keywords： Fluorescence nanoscopy     Super-resolution imaging     4Pi nanoscopy     IsoSTED     4Pi-SMLM    

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Effects of hypoxia inducible factor-1alpha siRNA on the invasion of human Hela cells and expression of

Bin YANG MS , Xianglin YUAN , Yanmei ZOU , Qingsong XI , Guoxian LONG , Qiang FU , Guangyuan HU MM ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 303-308 doi: 10.1007/s11684-009-0060-3

Abstract: on the invasion and the related protein expression of Hela cells and the role of hypoxia inducible factor

Keywords： hypoxia     actin     β     -catenin     E-cadherin     invasion    

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Preliminary Investigation of the Reversible 4D Printing of a Dual-Layer Component Article

Amelia Yilin Lee, Jia An, Chee Kai Chu, Yi Zhang

Engineering 2019, Volume 5, Issue 6,   Pages 1159-1170 doi: 10.1016/j.eng.2019.09.007

Abstract: manufacturing and advances in shape memory materials have fueled the progress of four-dimensional (4DWith increasing improvements in design, reversible 4D printing—or two-way 4D printing—hasneed for human interference, as the programming is completely driven by external stimuli, which allows 4D-printedThis study proposes a new reversible 4D printing actuation method.This understanding of the curvature will provide a great degree of control over the reversible 4D-printed

Keywords： 4D printing     Additive manufacturing     Shape memory polymer     Reversible 4D printing     Two-way 4D printing    

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Title Author Date Type Operation

Transcription Factors HNF1A, HNF4A, and FOXA2 Regulate Hepatic Cell Protein N-Glycosylation

Vedrana Vičić Bočkor,Nika Foglar,Goran Josipović,Marija Klasić,Ana Vujić,Branimir Plavša,Toma Keser,Samira Smajlović,Aleksandar Vojta,Vlatka Zoldoš

Journal Article

Relationship between expression of hepatocyte grow factor and apoptosis of trophoblasts in hypertensive

OUYANG Shan, ZHANG Qinghua, QIAO Fuyuan

Journal Article

carcinoma progression by repressing translation through the interaction with eukaryotic initiation factor4A-I

Journal Article

DDB1- and CUL4-associated factor 8 plays a critical role in spermatogenesis

Xiuli Zhang, Zhizhou Xia, Xingyu Lv, Donghe Li, Mingzhu Liu, Ruihong Zhang, Tong Ji, Ping Liu, Ruibao Ren

Journal Article

ZnFe2O4/BiVO4 Z-scheme heterojunction for efficient visible-light photocatalytic

Journal Article

Inhibition of TNF-alpha secretion from peripheral blood monocular cells by triptolid is associated withTNF-alpha-308 gene polymorphisms in rheumatoid arthritis patients

Xiu-Liang TAO MM, Sheng-Hao TU MD, Ri-Bo XIONG MM, Yong-Hong HU BM,

Journal Article

Li4SiO4-coated LiNi0.5Mn1.5O4 as the high performance

Shifeng YANG, Wenfeng REN, Jian CHEN

Journal Article

Enhanced debromination of 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) by zero-valent zinc with ascorbic

Chaojin Jiang, Xiaoqian Jiang, Lixun Zhang, Yuntao Guan

Journal Article

Knockdown of RFC4 inhibits the cell proliferation of nasopharyngeal carcinoma and

Journal Article

Laws of 4D Printing

Farhang Momeni, Jun Ni

Journal Article

Synthesis, insecticidal activities and DFT study of pyrimidin-4-amine derivatives containing the 1,2,4

Journal Article

Identifying stakeholders’ roles and relevant project documents for 4D-based collaborative decision making

Veronika BOLSHAKOVA, Annie GUERRIERO, Gilles HALIN

Journal Article

Review of 4Pi Fluorescence Nanoscopy

Xiang Hao, Yiming Li, Shuang Fu, Yanghui Li, Yingke Xu, Cuifang Kuang, Xu Liu

Journal Article

Effects of hypoxia inducible factor-1alpha siRNA on the invasion of human Hela cells and expression of

Bin YANG MS , Xianglin YUAN , Yanmei ZOU , Qingsong XI , Guoxian LONG , Qiang FU , Guangyuan HU MM ,

Journal Article

Preliminary Investigation of the Reversible 4D Printing of a Dual-Layer Component

Amelia Yilin Lee, Jia An, Chee Kai Chu, Yi Zhang

Journal Article